Talking Heads
Much research has been done lately about 'talking head' simulations. These simulations attempt to present a realistic animation of a person while they are talking, such that the movement of the lips, and the visibility of the tongue give cues as to what is being said. This can help hearing impaired as well as help the general listener improve understanding.
One talking head system developed at the University of Sheffield is described in the paper Image-based Talking Heads using Radial Basis Functions. More information about their research can be found on their Talking Heads Project Page. These folks are using FreeTTS too.